GHK-Cu (glycyl-L-histidyl-L-lysine : copper(II)) is an endogenous tripeptide that declines with age. It is one of the better-studied cosmetic peptides, with published in vitro and small clinical work on wound healing, collagen synthesis and skin remodelling.
Used topically in many skincare formulations; subcutaneous use is discussed informally but has less supporting evidence.
This entry is informational only.